GeneSplicer: a new computational method for splice site prediction.

M Pertea; X Lin; S L Salzberg

doi:10.1093/nar/29.5.1185

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GeneSplicer: a new computational method for splice site prediction.

M Pertea·X Lin·S L Salzberg

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Abstract

GeneSplicer is a new, flexible system for detecting splice sites in the genomic DNA of various eukaryotes. The system has been tested successfully using DNA from two reference organisms: the model plant Arabidopsis thaliana and human. It was compared to six programs representing the leading splice site detectors for each of these species: NetPlantGene, NetGene2, HSPL, NNSplice, GENIO and SpliceView. In each case GeneSplicer performed comparably to the best alternative, in terms of both accuracy and computational efficiency.

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Algorithms Alternative Splicing Arabidopsis Computational Biology DNA Databases, Factual Genes Genome, Human Genome, Plant Humans Journal Article Research Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.

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M Pertea, X Lin, S L Salzberg. 2001-03-01. GeneSplicer: a new computational method for splice site prediction.. https://doi.org/10.1093/nar%2F29.5.1185

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