Pluripotent hematopoietic stem cell development during embryogenesis.

A Cumano; I Godin

doi:10.1016/s0952-7915(00)00200-4

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Pluripotent hematopoietic stem cell development during embryogenesis.

A Cumano·I Godin

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Abstract

Significant progress has been made towards a better understanding of the establishment of hematopoiesis in the embryo. Hematopoietic precursors have been shown to arise independently in the yolk sac and in the intra-embryonic mesoderm. From the combined analysis of differentiation potentials, expression patterns and mutant phenotypes, a picture has emerged: definitive hematopoietic precursors are transiently generated in a specific environment close to the endothelium of the main arteries.

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Animals Cell Differentiation Cell Lineage Embryo, Mammalian Endothelium, Vascular Hematopoiesis Hematopoietic Stem Cells Humans Transcription Factors Journal Article Review

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A Cumano, I Godin. 2001. Pluripotent hematopoietic stem cell development during embryogenesis.. https://doi.org/10.1016/s0952-7915(00)00200-4

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