Expressing the human genome.

R Tupler; G Perini; M R Green

doi:10.1038/35057011

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Expressing the human genome.

R Tupler·G Perini·M R Green

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Abstract

We have searched the human genome for genes encoding new proteins that may be involved in three nuclear gene expression processes: transcription, pre-messenger RNA splicing and polyadenylation. A plethora of potential new factors are implicated by sequence in nuclear gene expression, revealing a substantial but selective increase in complexity compared with Drosophila melanogaster and Caenorhabditis elegans. Although the raw genomic information has limitations, its availability offers new experimental approaches for studying gene expression.

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Animals Gene Expression Genome, Human Human Genome Project Humans Poly A RNA Splicing Transcription Factors Transcription, Genetic Transcriptional Activation Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

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R Tupler, G Perini, M R Green. 2001-02-15. Expressing the human genome.. https://doi.org/10.1038/35057011

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