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PubMed · 11241061

Ophthalmic drops causing coma in an infant.

R J Berlin·U T Lee·J R Samples·L F Rich·D D Tang-Liu·K A Sing·R D Steiner
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Abstract

A 1-month-old infant with Peters anomaly had recurrent episodes of unresponsiveness, hypotension, hypotonia, hypothermia, and bradycardia. An extensive medical evaluation determined these episodes to be caused by brimonidine, an anti-glaucoma agent. There is the potential for serious toxic effects from the systemic absorption of topically applied ophthalmic agents in children.

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Adrenergic alpha-AgonistsBrimonidine TartrateComaEye AbnormalitiesHumansInfant, NewbornMaleOphthalmic SolutionsPractice Guidelines as TopicQuinoxalinesSyndromeCase ReportsJournal Article

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R J Berlin, U T Lee, J R Samples, L F Rich, D D Tang-Liu, K A Sing, R D Steiner. 2001. Ophthalmic drops causing coma in an infant.. https://doi.org/10.1067/mpd.2001.111319

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