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PubMed · 1124747

Clindamycin-associated colitis.

J L Unger·W E Penka·C Lyford
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Abstract

Four cases of clindamycin-associated colitis have recently been observed at Kansas University Medical Center. There have been a few reports in the literature of colitis associated with this antibiotic, and our 4 cases are similar to those noted previously. All had the onset of diarrhea 7-14 days following the initiation of clindamycin therapy; the diarrhea persisted for weeks after the drug was discontinued. Mucosal changes ranged from focal ulceration to pseudomembrane formation. Diarrhea in a patient on clindamycin should alert the physician to the possibility of antibiotic induced colitis, a condition with significant morbidity and occasional mortality.

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AdenocarcinomaAdministration, OralAdultAgedCephalothinClindamycinColitisColonDiarrheaFemaleFinger InjuriesHumansLung NeoplasmsMaleMiddle AgedPneumoniaPostoperative ComplicationsPrednisoneRespiratory Tract InfectionsJournal Article

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J L Unger, W E Penka, C Lyford. 1975. Clindamycin-associated colitis.. https://doi.org/10.1007/bf01070724

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