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PubMed · 11249694

VP-14637 ViroPharma.

J McKimm-Breschkin
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Abstract

VP-14637 is the lead compound in a series of low molecular weight viral replication inhibitors which are under preclinical investigation by ViroPharma for the potential treatment of RSV infection [322651]. Phase I trials designed to evaluate the safety and pharmacokinetic prpfile of VR-14637 in healthy human volunteers have begun [385870]. VP-14637 is most active against pneumoviruses and the available data suggest that it is an inhibitor of RSV viral fusion activity [363716], [361097].

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AnimalsAntiviral AgentsClinical Trials as TopicDrugs, InvestigationalHumansHydrazonesPhenolsRespiratory Syncytial Virus InfectionsRespiratory Syncytial Virus, HumanStructure-Activity RelationshipTetrazolesJournal Article

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J McKimm-Breschkin. 2000. VP-14637 ViroPharma.. https://pubmed.ncbi.nlm.nih.gov/11249694/

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