Morphological correlates of functionally defined synaptic vesicle populations.

T Schikorski; C F Stevens

doi:10.1038/86042

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Morphological correlates of functionally defined synaptic vesicle populations.

T Schikorski·C F Stevens

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Abstract

By combining photoconversion of FM1-43-stained vesicles and electron microscopy of hippocampal synapses, we find evidence that the population of morphologically docked synaptic vesicles corresponds to the release-ready neurotransmitter quanta. Furthermore, those synaptic vesicles that are participating in cycles of exo- and endocytosis tend to be closer to the active zone than vesicles that are being held in reserve.

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Animals Cells, Cultured Fluorescent Dyes Hippocampus Image Processing, Computer-Assisted Neurons Neurotransmitter Agents Pyridinium Compounds Quaternary Ammonium Compounds Rats Regression Analysis Synapses Synaptic Vesicles Journal Article

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T Schikorski, C F Stevens. 2001. Morphological correlates of functionally defined synaptic vesicle populations.. https://doi.org/10.1038/86042

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