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Caspases: more than just killers?

M Los·C Stroh·R U Jänicke·I H Engels·K Schulze-Osthoff
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Abstract

Proteases of the caspase family constitute the central executioners of apoptosis. Several recent observations suggest that caspases and apoptosis-regulatory molecules exert important functions beyond that of cell death, including the control of T-cell proliferation and cell-cycle progression. Here, Los and colleagues propose a model that directly connects cell suicide mechanisms to the regulation of cell-cycle progression.

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AnimalsApoptosisCaspasesHumansT-LymphocytesJournal ArticleReview

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M Los, C Stroh, R U Jänicke, I H Engels, K Schulze-Osthoff. 2001. Caspases: more than just killers?. https://doi.org/10.1016/s1471-4906(00)01814-7

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