Activity modulates neuronal proliferation in the developing olfactory epithelium.

J M Mirich; P C Brunjes

doi:10.1016/s0165-3806(01)00101-8

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Activity modulates neuronal proliferation in the developing olfactory epithelium.

J M Mirich·P C Brunjes

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Abstract

The present experiment demonstrates that environmental stimulation can activate neurogenesis within olfactory mucosae exhibiting depressed proliferation. Rats underwent naris occlusion on P1 with plugs that were removed 20 days later. Normal respiration induced a sharp increase in proliferating neuronal precursors within 24-48 h, and epithelial depth was restored within 5 days.

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Animals Cell Division Olfactory Receptor Neurons Rats Rats, Long-Evans Sensory Deprivation Smell Journal Article Research Support, U.S. Gov't, P.H.S.

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J M Mirich, P C Brunjes. 2001-03-29. Activity modulates neuronal proliferation in the developing olfactory epithelium.. https://doi.org/10.1016/s0165-3806(01)00101-8

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