Genetic interference in protozoa.

P Bastin; A Galvani; L Sperling

doi:10.1016/s0923-2508(01)01182-2

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PubMed · 11316365

Genetic interference in protozoa.

P Bastin·A Galvani·L Sperling

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Abstract

RNA interference first described in Caenorhabditis elegans and transgene-induced post-transcriptional gene silencing first described in plants and fungi now appear as different means of activating a conserved and ancient mechanism that can protect genomes against viruses and transposons and perhaps also control expression of endogenous genes. We present here similar genetic interference phenomena in highly divergent protozoa, Trypanosoma and Paramecium, and look ahead to what contribution these microorganisms could bring to this fast-moving area.

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Animals Gene Silencing Genes, Protozoan Leishmania Paramecium RNA, Antisense RNA, Double-Stranded RNA, Protozoan Trypanosoma Journal Article Research Support, Non-U.S. Gov't Review

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P Bastin, A Galvani, L Sperling. 2001. Genetic interference in protozoa.. https://doi.org/10.1016/s0923-2508(01)01182-2

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