Prostate-specific antigen-all that rises is not refractory.

B L Hintz; A Van Nieuwenhuize; A R Kagan

doi:10.1016/s0090-4295(01)00911-6

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Prostate-specific antigen-all that rises is not refractory.

B L Hintz·A Van Nieuwenhuize·A R Kagan

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Abstract

After the initiation of androgen suppression in men with prostate cancer, the serum prostate-specific antigen (PSA) level generally declines. A subsequent PSA rise during that suppression usually reflects the presence of a significant component of hormonally refractory prostate cancer. We report a patient with a rising PSA level and elevated testosterone level after depot leuprolide in whom the PSA level subsequently declined with administration of bicalutamide.

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Adenocarcinoma Aged Androgen Antagonists Anilides Antineoplastic Agents Delayed-Action Preparations Humans Injections, Intramuscular Leuprolide Male Nitriles Prostate-Specific Antigen Prostatic Neoplasms Testosterone Tosyl Compounds Treatment Outcome Case Reports Journal Article

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B L Hintz, A Van Nieuwenhuize, A R Kagan. 2001. Prostate-specific antigen-all that rises is not refractory.. https://doi.org/10.1016/s0090-4295(01)00911-6

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