PubMed Health⌕ Search

PubMed · 11347430

Multi-position eye movement detection system.

Abstract

A device that records saccadic eye movements in any X-Y position is presented in this paper. Eye movements are recorded using infrared optoelectronics mounted on hemispherical shaped eyepieces, which in turn are mounted on goggles styled after an ophthalmologist's test frames. A computer controlled, wall mounted light bank facilitates targeting for eye movements. Output from the device is sent to a PC type computer and stored in the hard disk using a data acquisition board. The user interface is Windows based and the output from the goggles are represented as a trace map of plotted points. This output can also be saved or printed for future analysis and reference. The device is designed with reference to standard ISO design methodology, and subject safety and final product usage have been reviewed following ISO analysis procedures. Accuracy in tracking of eye movements is maintained by utilizing a twenty-four channel detection system, hemispherically mounted and lensed optoelectronics to reduce cross-talk due to incident light, and signal processing that attenuates incident light as well as ambient light. Also, a reset feature is included to maintain equal baseline control. An automatic switching device is included in the test frame to allow the device to "warm up," assuring that equal IR power is delivered for each subject tested. The IR units in the goggles are also modular in case replacement is required.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

W Pruehsner, J D Enderle. 2001. Multi-position eye movement detection system.. https://pubmed.ncbi.nlm.nih.gov/11347430/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

[Slide-based multi-parametric cytometry in ENT. Perspectives for the clinic and research].

BACKGROUND: Flow cytometry is the standard method for the multi-parametric analysis of cells. However, for about a decade, an instrument has been available which analyses fluorescing cells immobilised on slides called a laser scanning cytometer (LSC). Its design, according to the principles of slide-based cytometry, promises many advantages, especially in the analysis of minimal sample volumes. METHODS AND PATIENTS: To date, applications for cultured cells and animal models have been established. Its use for clinical purposes, however, remains to be critically evaluated. We analysed a variety of specimens obtained in our clinical routine. RESULTS: First, the instrument's resolution was evaluated using standardised particles. This showed a very good sensitivity across a wide range of fluorescence intensities at various wavelengths. Next, diverse applications for tissue engineering, immunophenotyping, and ENT-oncology were tested. Considering its microanalytical capacities, LSC proved to be a convincing tool for clinical use. Additionally, complex structures such as bi-layers of cultured cells were analysed. CONCLUSION: A broad spectrum of applications in clinical practice and research for the LSC is evident.

Equipment Design↗

Rectilinear ion trap: concepts, calculations, and analytical performance of a new mass analyzer.

A mass analyzer based on a rectilinear geometry ion trap (RIT) has been built, and its performance has been characterized. Design concepts for this type of ion trap are delineated with emphasis on the effects of electrode geometry on the calculated electric field. The Mathieu stability region was mapped experimentally. The instrument can be operated using mass-selective instability scans in both the boundary and resonance ejection versions. Comparisons of performance between different versions of the device having different dimensions allowed selection of an optimized geometry with an appropriate distribution of higher-order electric fields. Comparisons made under the same conditions between the performance of a conventional cylindrical ion trap and a RIT of 4 times greater volume show an improvement of 40 times in the signal-to-noise ratio resulting from the higher ion trapping capacity of the RIT. The demonstrated capabilities of the RIT include tandem mass spectrometry, a mass resolution in excess of 1000, and a mass/charge range of 650 Th, all in a simple structure that is only 3.5 cm(3) in internal volume.

Equipment Design↗

Electrowetting-based microfluidics for analysis of peptides and proteins by matrix-assisted laser desorption/ionization mass spectrometry.

A new technique for preparing samples for matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is reported. The technique relies on electrowetting-on-dielectric (EWOD) to move droplets containing proteins or peptides and matrix to specific locations on an array of electrodes for analysis. Standard MALDI-MS reagents, analytes, concentrations, and recipes are demonstrated to be compatible with the technique. Mass spectra are comparable to those collected by conventional methods. Nonspecific adsorption of analytes to device surfaces is demonstrated to be negligible. The results suggest that EWOD may be a useful tool for automating sample preparation for high-throughput proteomics and other applications of MALDI-MS.

Equipment Design↗