PubMed · 11351552
The source did not provide an abstract. Follow the original record for more information.
Explore connections, maps & timelines
S Tsotsos. 2000. Speech therapy for your computer.. https://pubmed.ncbi.nlm.nih.gov/11351552/
Cite the original work for its findings. Save a collection to share your selection of sources.
KEEP EXPLORING
We developed a multiplex, quantitative, real-time, polymerase chain reaction assay for cytomegalovirus (CMV) and used it to measure the CMV viral load in weekly blood specimens from 43 lung transplant recipients. The median viral load in blood samples immediately preceding bronchoscopy was 1150 copies/microg human DNA for 12 subjects with pneumonitis compared to 91 copies for 31 subjects without (P=0.02, Mann-Whitney U test). Each log10 increase in CMV viral load resulted in an increase of 1.92 in the odds ratio for CMV pneumonitis (95% confidence interval 1.03-3.56). CMV viral load was elevated (>100 copies/microg human DNA) for a median of 21 days before bronchoscopy in those subjects with pneumonitis versus 0 days in those without (P=0.004). We conclude that the risk of CMV pneumonitis after lung transplantation is related to the level of CMV DNA in blood. Quantitative PCR should be evaluated prospectively for the preemptive management of CMV in lung transplant recipients.
OBJECTIVE: To calculate the concordance of the computer record and the clinical history (CH) in preventive actions and health problems. DESIGN: Cross-sectional descriptive study. Quality evaluation. SETTING: Urban health centre with 31000 inhabitants. PATIENTS AND OTHER PARTICIPANTS: Randomised batch sample, with 14 cases for each of the 8 attendance base units with computerised records since 1997. N = 112. EXCLUSION CRITERIA: no visit later than January 1997 and absence of records in the CH or computer. MEASUREMENTS AND MAIN RESULTS: Through the checking of the records in the CH and computer, a mean concordance of 73.5 (95% CI, 66.8-80.2) for preventive actions and 93.5 for health problems (95% CI, 90.6-96.4) was found. There was a mean computer under-recording for health problems of 6.5% (95% CI, 3.62-9.32), and for preventive actions of 21% (95% CI, 9.1-33.3) only in those actions based on manual activity. However, in preventive actions based on verbal activity there was 14.3% mean CH under-recording (95% CI, 1.15-27.5). CONCLUSIONS: Concordance is not uniform, with under-recording for some parameters detected. This may affect the reliability and validity of health information in these records. We believe that the way data are collected determines this to a large extent. We suggest as corrective measures improving the training and incentives of health professionals, making computer programmes more appropriate to their purpose and standardising data collection in primary care CR.
Explore the source record for details and available documents.