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DXS101: a highly polymorphic X-linked STR.

J Edelmann·R Szibor
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Abstract

This paper presents sequence and population genetic data for the microsatellite marker DXS101 which is a highly polymorphic X-linked trinucleotide polymorphism with 18 alleles 179-233 bp in length. A polymorphism information content (PIC) of 0.884 and a mean exclusion chance (MEC) of 0.879 were obtained by analysing a Caucasian population sample. A deviation from the Hardy-Weinberg equilibrium (HWE) could not be detected. Kinship tests revealed a typical X-linked inheritance and no mutations were found in 340 meioses. DXS101 is located 104.9-121 cM from the Xp-telomere (Xp-tel) corresponding to Xq21.33-Xq22.3. Concomitant testing of DXS101 and DXS6807 is possible as these two markers are unlinked. The data presented qualify this X-linked microsatellite marker as a useful tool for forensic purposes.

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ChildChromosome MappingDNA FingerprintingFemaleGene FrequencyGenetic LinkageGermanyHumansMalePaternityPolymorphism, GeneticTrinucleotide RepeatsWhite PeopleX ChromosomeJournal Article

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J Edelmann, R Szibor. 2001. DXS101: a highly polymorphic X-linked STR.. https://doi.org/10.1007/s004140000188

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