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New artificial siderophores based on a monosaccharide scaffold.

S Heggemann·M Schnabelrauch·D Klemm·U Möllmann·R Reissbrodt·L Heinisch
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Abstract

New artificial catecholate siderophores with methyl alpha-D-glucopyranoside as scaffold were synthesized. The dihydroxy- or di(acetoxy)benzoyl moieties were attached either directly or via aminopropyl spacer groups, to the carbohydrate scaffold. The siderophore activity of the prepared siderophore analogs was examined by a growth promotion assay using various Gram-negative bacteria and mycobacteria and by the CAS-assay.

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Gram-Negative BacteriaMagnetic Resonance SpectroscopyMethylglucosidesMolecular StructureMycobacteriumSiderophoresSpectrometry, Mass, Electrospray IonizationJournal ArticleResearch Support, Non-U.S. Gov't

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S Heggemann, M Schnabelrauch, D Klemm, U Möllmann, R Reissbrodt, L Heinisch. 2001. New artificial siderophores based on a monosaccharide scaffold.. https://doi.org/10.1023/a%3A1016689807111

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