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Morpholino antisense oligonucleotides: tools for investigating vertebrate development.

D R Corey·J M Abrams
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Abstract

Antisense oligonucleotides provide a promising approach to investigating gene function in vivo, but their ability to offer unambiguous insights into phenotypes has been debated. The recent use of morpholino antisense oligonucleotides in zebrafish embryos may prove a major advance, but rigorous controls are essential.

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AnimalsGene Expression Regulation, DevelopmentalMorpholinesOligonucleotides, AntisenseRNA, MessengerSea UrchinsZebrafishJournal ArticleResearch Support, U.S. Gov't, P.H.S.Review

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D R Corey, J M Abrams. 2001-04-26. Morpholino antisense oligonucleotides: tools for investigating vertebrate development.. https://doi.org/10.1186/gb-2001-2-5-reviews1015

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