PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 11388327

[Heart rate variability].

S Guzzetti
View original source ↗Export metadata ↓

Abstract

In 1981 a study on heart rate variability (HRV) and on the neural control of the heart was published in Science. Since then, the number of papers concerning this topic has increased exponentially. Some aspects of the relationship between HRV and the neural control of the cardiovascular system are now clear, for example: a decreased SDNN (a measure of variance) during a period of 24 hours is a well established independent negative prognostic factor after acute myocardial infarction and in chronic heart failure patients. Moreover, an increased sympathetic modulation elicited by standard laboratory maneuvers determines an increased power of the low frequency (LF) spectral component (0.03-0.15 Hz), expressed in normalized units. Nevertheless, the interpretation of the oscillatory components present in HRV, particularly in pathophysiological conditions, is far from being clear. The influence of several neurohumoral circuits can induce various changes in HRV according to different physiological or pathological conditions. A new approach to the study of HRV called "information domain" might help to obtain some more information about HRV. Furthermore, in the future, HRV analysis might be useful when deciding on the best pharmacological combination for the individual patient and for the probabilistic prediction of acute cardiac events.

Explore related subjects

Heart RateHumansTime FactorsEnglish AbstractJournal ArticleReview

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

S Guzzetti. 2001. [Heart rate variability].. https://pubmed.ncbi.nlm.nih.gov/11388327/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2002

The humour effect: differential processing and privileged retrieval.

The effects of humour on memory and heart rate were explored as a function of experimental design. In within-subject manipulations, original humorous cartoons were better remembered than the literal translations and weird cartoons, whereas literal and weird cartoons were equally well remembered. Good recall of humorous cartoons occurred at the expense of recall of non-humorous cartoons. Secondary heart-rate deceleration was larger in response to original cartoons than to literal and weird cartoons. Neither the memory nor the heart-rate effects were found in between-subjects comparisons. The results were consistent with differential processing resulting from within-list contrasts. However, retrieval processes also favoured good recall of humorous material.

Heart Rate↗
PubMed2002

Can mandibular advancement devices be a satisfactory substitute for short term use in patients on nasal continuous positive airway pressure?

BACKGROUND: Mandibular advancement devices (MADs) can successfully control both snoring and obstructive sleep apnoea (OSA). Many patients on nasal continuous positive airway pressure (NCPAP) for OSA would like a more portable alternative, even if only temporarily. This study assesses what proportion of patients with OSA already on NCPAP can successfully use a MAD for short periods (up to 1 month) as a temporary alternative to NCPAP. METHODS: Fifty patients with OSA, already on NCPAP for at least 3 months, were recruited by invitation. They were provided with a simple fixed MAD estimated to provide 75% of maximum mandibular protrusion. Sleep studies using a portable home recorder were performed on and after three nights without NCPAP to provide control data. Following acclimatisation to the MAD, sleep studies were also planned after 3, 7, and 28 days while using the MAD. If their overnight >4% SaO(2) dips per hour deteriorated to >20 or the Epworth sleepiness score (ESS) rose to >9 (or increased by >4 over baseline) on nights 3 or 7, they were then deemed to have failed the trial and were withdrawn. RESULTS: Of the 50 patients entered, one had inadequate teeth for a MAD and 31 gave up trying to use the device during the acclimatisation period because of side effects. Of the 18 prepared to use the device, two patients failed at night 3, five at night 7, and two at night 28. Thus, nine patients remained controlled by our criteria at night 28. On average, sleep study indices while using the MAD were poor compared with the night on NCPAP. CONCLUSIONS: Simple MADs are poorly tolerated by patients with OSA already on NCPAP. OSA was adequately controlled by our criteria in 32% of those recruited for the equivalent of a weekend, in 22% for 1 week, and in 18% for up to 1 month. Better tolerated devices would be likely to improve on these figures.

Heart Rate↗