Single molecule nanobioscience.

A Ishijima; T Yanagida

doi:10.1016/s0968-0004(01)01860-6

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PubMed · 11440856

Single molecule nanobioscience.

A Ishijima·T Yanagida

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Abstract

In recent years, the rapid development and progress of single-molecule detection techniques have opened up a new era of biological research. The advantage of single-molecule studies is that data are not obscured by the ensemble-averaged measurements inherent in classical biochemical experiments. These techniques are shedding light on the dynamic and mechanistic properties of molecular machines, both in vivo and in vitro. This review summarizes the single-molecule experiments that have been designed to investigate molecular motors, enzyme reactions, protein dynamics, DNA transcription and cell signaling.

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Actins Adenosine Triphosphatases Animals Biotechnology DNA Humans Ion Channels Kinesins Microscopy, Fluorescence Models, Biological Myosins Signal Transduction Transcription, Genetic Journal Article Review

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A Ishijima, T Yanagida. 2001. Single molecule nanobioscience.. https://doi.org/10.1016/s0968-0004(01)01860-6

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