[Physical exercise and insulin sensitivity].

J F Gautier; F Mauvais-Jarvis

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PubMed · 11452219

[Physical exercise and insulin sensitivity].

J F Gautier·F Mauvais-Jarvis

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Abstract

Physical exercise is known to be essential in the treatment of type 2 diabetes. An increased glucose uptake is evidenced during acute muscular exercise, over the post-exercise period, and following physical training. In this paper, we review metabolic and molecular aspects of physical exercise. We emphasize on the non-insulin dependent glucose transport induced by muscular contraction, which involves AMP-activated protein kinase. The discovery of this pathway is likely to open new therapeutic targets for type 2 diabetes.

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Biological Transport Cyclic AMP-Dependent Protein Kinases Diabetes Mellitus, Type 2 Exercise Glucose Glucose Transporter Type 1 Glucose Transporter Type 4 Humans Insulin Resistance Monosaccharide Transport Proteins Muscle Contraction Muscle Proteins Muscle, Skeletal English Abstract Journal Article Review

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J F Gautier, F Mauvais-Jarvis. 2001. [Physical exercise and insulin sensitivity].. https://pubmed.ncbi.nlm.nih.gov/11452219/

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