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[Dendritic cells and interaction with other cell types. Immune tolerance].

S Guerder
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Abstract

T cell tolerance to self antigen is mainly established in the thymus were self-reactive T cells are deleted. Interdigitating dendritic cells and medulary epithelial cells are directly involved in the deletion process. Some self-reactive T cells escape, however this thymic censorship and enter the peripheral pool of naive T cells. Multiple mechanisms are also at play in the periphery to control this potentially armfull T cells, this include deletion and immune deviation.

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AnimalsAutoantigensDendritic CellsHumansImmune ToleranceT-LymphocytesThymus GlandEnglish AbstractJournal ArticleReview

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BibTeXRIS

S Guerder. 2001. [Dendritic cells and interaction with other cell types. Immune tolerance].. https://doi.org/10.1016/s0369-8114(01)00169-9

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