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PubMed · 1151635

Mathematical formulation for nonuniform multiple dosing.

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J R Howell. 1975. Mathematical formulation for nonuniform multiple dosing.. https://doi.org/10.1002/jps.2600640328

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The evaluation of the sphero-cylindrical components of curvature or refraction from measurements taken along three distinct meridians has been solved for various sets of three fixed meridians. A constraint of those solutions has been that the meridians of measurement are necessarily predetermined, which introduces an unwelcome restriction in experimental or clinical applications of tri-meridional analysis. A new solution is presented (in three formats: analogue computer, graphical and algebraic), which enables any set of three meridians to be used for tri-meridional analysis. A computer program listing (in BASIC) is included.

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