Thymol derivatives from Eupatorium fortunei.

M Tori; Y Ohara; K Nakashima; M Sono

doi:10.1021/np0101191

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Thymol derivatives from Eupatorium fortunei.

M Tori·Y Ohara·K Nakashima·M Sono

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Abstract

Sixteen new thymol derivatives have been isolated from Eupatorium fortunei and their structures determined based on spectroscopic data. They were classified into three groups (i-iii) depending on the oxidation levels: (i) one oxygen function at the 9-position, (ii) two oxygen functions at the 8- and 9-positions, and (iii) three oxygen functions at the 8-, 9-, and 10-positions. The hydroxyl groups are acylated with tigloyl, angeloyl, acetyl, isobutyryl, 3-methyl-2-butenoyl, or 2-methylbutyryl moieties. The compounds having chiral centers showed no specific rotation and exist as racemic mixtures.

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Chromatography, High Pressure Liquid Japan Magnetic Resonance Spectroscopy Molecular Structure Plants, Medicinal Spectrophotometry, Infrared Thymol Journal Article

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M Tori, Y Ohara, K Nakashima, M Sono. 2001. Thymol derivatives from Eupatorium fortunei.. https://doi.org/10.1021/np0101191

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