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PubMed · 11520233

Two phenanthraquinones from Dendrobium moniliforme.

T H Lin·S J Chang·C C Chen·J P Wang·L T Tsao
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Abstract

Two phenanthraquinones were isolated from the stems of Dendrobium moniliforme. They were identified by interpretation of spectral data as 2,6-dimethoxy-1,4,5,8-phenanthradiquinone and 5-hydroxy-3,7-dimethoxy-1,4-phenanthraquinone, named moniliformin (1) and denbinobin (2), respectively. This is the first report of compound 1, which possesses a novel 1,4,5,8-diquinone moiety in the phenanthraquinone skeleton. Compound 2 showed potent antiinflammatory effects in vitro.

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AnimalsAnthraquinonesAnti-Inflammatory Agents, Non-SteroidalAscitic FluidCells, CulturedChromatography, Thin LayerDinoprostoneGlucuronidaseHistamineInterferon-gammaLipopolysaccharidesMacrophagesMagnetic Resonance SpectroscopyMast CellsMiceMicrogliaMolecular StructureNitric OxidePhenanthrenesPlant StemsPlants, MedicinalQuinacrineRatsSpectrophotometry, InfraredSpectrophotometry, UltravioletSpectroscopy, Fourier Transform InfraredTaiwanTumor Necrosis Factor-alphaJournal ArticleResearch Support, Non-U.S. Gov't

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T H Lin, S J Chang, C C Chen, J P Wang, L T Tsao. 2001. Two phenanthraquinones from Dendrobium moniliforme.. https://doi.org/10.1021/np010016i

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