NMR studies of prebiotic polypertides.

S Andini; E Benedetti; L Ferrara; L PAOLILLO; P A Temussi

doi:10.1007/bf01372399

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NMR studies of prebiotic polypertides.

S Andini·E Benedetti·L Ferrara·L PAOLILLO·P A Temussi

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Abstract

Several polypeptides prepared by means of pyrocondensation have been the subject of structural investigations. Attention has been focused on the constitutional characterization of homo-and co-polymers containing Asp and Glu residues, whose role is essential for the formation of the so-called proteinoids. Contrary to the literature data based on chemical degradation, nmr studies show conclusively that in thermal poly-aspartic acid only beta-peptide linkages are present. This result casts serious doubt on the role thermal condensation might have played in prebiotic polypeptide syntheses.

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Aspartic Acid Glutamates Glycine Magnetic Resonance Spectroscopy Molecular Conformation Peptides Journal Article

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S Andini, E Benedetti, L Ferrara, L PAOLILLO, P A Temussi. NMR studies of prebiotic polypertides.. https://doi.org/10.1007/bf01372399

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