Syndecan-4 and focal adhesion function.

A Woods; J R Couchman

doi:10.1016/s0955-0674(00)00254-4

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Syndecan-4 and focal adhesion function.

A Woods·J R Couchman

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Abstract

Two groups have now reported the viability of mice that lack syndecan-4. These mice have wound healing/angiogenesis problems, and fibroblasts from these animals differ in adhesion and migration from normal. This is consistent with recent in vitro data indicating a need for signaling via syndecan-4 for focal adhesion formation, and reports that overexpression of proteins that bind syndecan-4 can modify cell adhesion and migration.

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Animals Focal Adhesions Integrins Membrane Glycoproteins Mice Mice, Knockout Models, Biological Neovascularization, Pathologic Protein Structure, Tertiary Proteoglycans Signal Transduction Syndecan-4 Wound Healing Journal Article Research Support, U.S. Gov't, P.H.S.Review

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A Woods, J R Couchman. 2001. Syndecan-4 and focal adhesion function.. https://doi.org/10.1016/s0955-0674(00)00254-4

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