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PubMed · 11545261

GABA signalling during development: new data and old questions.

P Varju·Z Katarova·E Madarász·G Szabó
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Abstract

In addition to being the major inhibitory neurotransmitter, gamma-aminobutyric acid (GABA) is thought to play a morphogenetic role in embryonic development. During the last decade, considerable progress has been made in elucidating the molecular mechanisms involved in GABA synthesis and biological action. The present review is an attempt to summarise recent results on the ontogeny of the different components of embryonic GABA signalling with an emphasis on the synthesis of GABA by different molecular forms of glutamic acid decarboxylase (GAD).

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AnimalsCarrier ProteinsCell DivisionCell MembraneCell MovementCentral Nervous SystemGABA Plasma Membrane Transport ProteinsGlutamate DecarboxylaseGrowth ConesHumansMembrane ProteinsMembrane Transport ProteinsMutagenesisNeuronsOrganic Anion TransportersSignal TransductionStem Cellsgamma-Aminobutyric AcidJournal ArticleReview

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P Varju, Z Katarova, E Madarász, G Szabó. 2001. GABA signalling during development: new data and old questions.. https://doi.org/10.1007/s004410100356

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