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PubMed · 11551470

In vitro display technologies: novel developments and applications.

P Amstutz·P Forrer·C Zahnd·A Plückthun
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Abstract

In vitro display techniques are powerful tools to select polypeptide binders against various target molecules. Novel applications include maturation of protein affinity and stability, selection for enzymatic activity, and the display of cDNA and random polypeptide libraries. Taken together, these display techniques have great potential for biotechnological, medical and proteomic applications.

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Binding SitesDNA, ComplementaryDirected Molecular EvolutionDrug Evaluation, PreclinicalEnzyme StabilityGene LibraryMutagenesisPeptide LibraryProteinsRNA, MessengerRibosomesJournal ArticleReview

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P Amstutz, P Forrer, C Zahnd, A Plückthun. 2001. In vitro display technologies: novel developments and applications.. https://doi.org/10.1016/s0958-1669(00)00234-2

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