Donitriptan (Pierre Fabre).

M Dukat

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PubMed · 11575714

Donitriptan (Pierre Fabre).

M Dukat

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Abstract

Pierre Fabre is developing donitriptan, a piperazide 5-HT1D agonist, as a potential treatment for migraine [175854]. In January 2001, donitriptan had completed phase I trials for migraine and was scheduled to enter phase II development [396027]. This compound has an increased potency and, importantly, markedly higher intrinsic activity in comparison to the well described tryptamine derivatives, naratriptan, zolmitriptan and sumatriptan [295769].

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Animals Clinical Trials, Phase I as Topic Drug Evaluation, Preclinical Drugs, Investigational Humans Migraine Disorders Molecular Structure Nitriles Piperazines Serotonin Receptor Agonists Tryptamines Comparative Study Journal Article

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M Dukat. 2001. Donitriptan (Pierre Fabre).. https://pubmed.ncbi.nlm.nih.gov/11575714/

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