[Hypersensitivity pneumonitis].

V Spînu

PubMed · 11584680

[Hypersensitivity pneumonitis].

Abstract

Hypersensitivity pneumonitis (HP) is an interstitial lung disease associated with repeated exposure to a wide range of inhaled organic dusts and related occupational allergens. Immunological phenomena have been reported to play an essential role in initiating and maintaining the disease. Natural history, clinical findings, chest radiography, pulmonary function, immunological investigations, the use of the bronchoalveolar lavage, the prognostic and management of HP are discussed.

Explore related subjects

Adrenal Cortex Hormones Allergens Alveolitis, Extrinsic Allergic Biopsy Bronchoalveolar Lavage Fluid Diagnosis, Differential Humans Lung Prognosis Respiratory Function Tests English Abstract Journal Article Review

Keep this discovery

Explore connections, maps & timelines

BibTeX RIS

V Spînu. [Hypersensitivity pneumonitis].. https://pubmed.ncbi.nlm.nih.gov/11584680/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2008

Rituximab for treatment of opsoclonus-myoclonus syndrome in neuroblastoma.

Opsoclonus-myoclonus syndrome (OMS) is a rare paraneoplastic syndrome that occurs in 2%-3% of patients with neuroblastoma. The cause of this syndrome is believed to be immune mediated, but the exact mechanism still remains unclear. There is an urgent need to improve our current strategies for treating patients with OMS, as many patients have significant long-term neurologic deficits and behavior disorders with current treatment approaches. Therapies that have shown to improve symptoms in these patients have ranged from ACTH and corticosteroids, to intravenous gammaglobulin and plasmapheresis. We report our experience with Rituximab in a patient with neuroblastoma and OMS.

Adrenal Cortex Hormones↗

PubMed2007

Löffler endocarditis without peripheral eosinophilia.

Explore the source record for details and available documents.

Adrenal Cortex Hormones↗

PubMed2007

Cyclosporine sparing with mycophenolate mofetil, daclizumab and corticosteroids in renal allograft recipients: the CAESAR Study.

Although the calcineurin inhibitors (CNI) cyclosporine (CsA) and tacrolimus are highly effective immunosuppressants, they are associated with serious side effects. There is great interest in immunosuppressive regimens that permit reduction or elimination of CNIs, while maintaining adequate immunosuppression and acceptable acute rejection rates. Patients (n = 536) receiving their first renal allograft were randomized to one of three immunosuppressant regimens: daclizumab, mycophenolate mofetil (MMF), corticosteroids (CS) and low-dose CsA (target trough levels of 50-100 ng/mL), weaned from month 4 and withdrawn by month 6; daclizumab, MMF, CS and low-dose CsA; or MMF, CS and standard-dose CsA. Mean GFR 12 months after transplantation (primary end point) was not statistically different in the CsA withdrawal and low-dose CsA groups (both 50.9 mL/min/1.73 m(2)) vs. the standard-dose CsA group (48.6 mL/min/1.73 m(2)). At 12 months, the incidence of biopsy-proven acute rejection was significantly higher in the CsA withdrawal group (38%) vs. the low- or standard-dose CsA groups (25.4% and 27.5%, respectively; p < 0.05). In summary, a regimen of continuous low-dose CsA with MMF, CS and daclizumab induction is a clinically safe and effective immunosuppressive regimen in renal transplant recipients.

Adrenal Cortex Hormones↗