Combinatorial libraries and biological discovery.

N S Gray

doi:10.1016/s0959-4388(00)00257-9

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PubMed · 11595496

Combinatorial libraries and biological discovery.

N S Gray

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Abstract

Combinatorial chemistry has become a popular tool for the preparation of collections of compounds that can be used to find inhibitors and substrates for different protein targets. It has evolved to provide small molecule libraries, which, with the concomittant use of affinity chromatography, gene expression profiling and complementation, can be used to identify compounds and their protein targets in biological systems, including the neurological system.

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Animals Combinatorial Chemistry Techniques Gene Expression Profiling Humans Peptide Library Journal Article Review

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N S Gray. 2001. Combinatorial libraries and biological discovery.. https://doi.org/10.1016/s0959-4388(00)00257-9

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