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PubMed · 11597521

Recombinant vaccines for hepatitis E.

S U Emerson·R H Purcell
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Abstract

Hepatitis E virus causes epidemics of acute hepatitis in many developing countries. It infrequently causes disease in developed countries, but avirulent strains might circulate. Some evidence suggests that hepatitis E might be a zoonosis. There is probably only a single serotype. A candidate vaccine consisting of baculovirus-expressed recombinant capsid protein protected macaques from hepatitis E--it passed phase I clinical trials and is currently scheduled for phase II/III clinical trials.

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AnimalsClinical Trials as TopicDisease Models, AnimalHepatitis EHepatitis E virusHumansImmunotherapy, ActiveRecombinant ProteinsVaccines, SyntheticViral Hepatitis VaccinesViral ProteinsJournal ArticleReview

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S U Emerson, R H Purcell. 2001. Recombinant vaccines for hepatitis E.. https://doi.org/10.1016/s1471-4914(01)02106-2

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