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Abstract

Description is made of the various stages in the development of the problem. The earliest theories on atherosclerosis are discussed (Lobstein and others). Insofar development of the functional trend is concerned, the science of atherosclerosis is considered in the light of the classic works in the Russian medical literature of the second half of the XIXth century, mainly those of Botkin, Polotebnev etc. The author pays tribute also to the representatives of the French classical school (Euchart etc.). The problem of atherosclerosis is also dealt with in the light of recent advances of biochemistry, as well as in the light of the statements of A. L. Miasnikov on the issue about the relationship between atherosclerosis and hypertonia and his classification of atherosclerosis.