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PubMed · 1166074

Hydroxyurea-induced erythroid differentiation.

N J Rencricca·B S Morse·F C Monette·D Howard·F Stohlman
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Abstract

Hydroxyurea, a cytotoxic agent which destroys cells in DNA synthesis, has been shown to evoke the differentiation of a small number of hemopoietic precursor cells in the erythroid series of erythropoietically suppressed hypertransfused mice. This effect does not appear to be mediated by erythropoietin (EP) since the simultaneous injection of anti-EP did not alter this response.

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AnimalsAntibodiesCell CountErythropoietinFemaleHematocritHematopoietic Stem CellsHydroxyureaMicePolycythemiaReticulocytesJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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N J Rencricca, B S Morse, F C Monette, D Howard, F Stohlman. 1975. Hydroxyurea-induced erythroid differentiation.. https://doi.org/10.3181/00379727-149-38956

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