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PubMed · 11697731

Cytochrome P450 pattern revision.

A G Buchatskii·Kazachenko KYu·A A Alexandrov
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Abstract

The pattern suggested for the structure-function superfamily of cytochromes P450 is composed by combining the conserved amino acid motifs. The sizes of P450 cytochromes were estimated according to their length. The empirical coefficients reflecting the peculiarities of the primary structure of these enzymes are calculated. We propose an approach for determining novel proteins sequences to the mentioned superfamily on the ground of the complex of these parameters. A number of the hypothetical proteins from the international databases is related to the cytochromes P450 by means of our pattern.

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Amino Acid SequenceCytochrome P-450 Enzyme SystemDatabases, ProteinHumansMolecular Sequence DataPattern Recognition, AutomatedSequence AlignmentComparative StudyJournal ArticleResearch Support, Non-U.S. Gov't

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A G Buchatskii, Kazachenko KYu, A A Alexandrov. 2001. Cytochrome P450 pattern revision.. https://doi.org/10.1080/07391102.2001.10506737

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