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Leptin and puberty.

H F Urbanski
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Abstract

Leptin is thought to relay metabolic information to the hypothalamic-pituitary- gonadal axis and to participate in the neuroendocrine control of puberty. To help elucidate the underlying mechanism, Cheung et al. recently performed a diverse series of experiments, the results of which undermine the prevailing hypothesis that leptin acts as a metabolic trigger for the initiation of puberty. Instead, their results suggest that leptin is one of many permissive metabolic factors that allow pubertal development to proceed.

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AnimalsCarrier ProteinsFemaleHumansLeptinMaleMicePubertyRNA, MessengerRatsReceptors, Cell SurfaceReceptors, LeptinNews

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H F Urbanski. 2001. Leptin and puberty.. https://doi.org/10.1016/s1043-2760(01)00505-7

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