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PubMed · 11703847

Controlling malaria: challenges and solutions.

P Olliaro·W R Taylor·J Rigal
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Abstract

Antimalarial drug resistance is a major public health challenge and the principal reason for the erosion of efficacious treatments. Cost and the limited number of antimalarial drugs in current use impose considerable constraints on malaria control, especially in sub-Saharan Africa. The paper describes a multilateral, multidisciplinary research project on artemisinin-based combination therapy, which offers a new and potentially highly effective way to prevent or retard the development of drug resistance.

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Advisory CommitteesAfrica South of the SaharaAntimalarialsArtemisininsBiomarkersDrug ResistanceDrug Therapy, CombinationEndpoint DeterminationEpidemiologic Research DesignHumansMalariaMulticenter Studies as TopicRandomized Controlled Trials as TopicSesquiterpenesTreatment OutcomeWorld Health OrganizationJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.

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P Olliaro, W R Taylor, J Rigal. 2001. Controlling malaria: challenges and solutions.. https://doi.org/10.1046/j.1365-3156.2001.00752.x

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