Computational protein design.

C M Kraemer-Pecore; A M Wollacott; J R Desjarlais

doi:10.1016/s1367-5931(01)00267-8

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Computational protein design.

C M Kraemer-Pecore·A M Wollacott·J R Desjarlais

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Abstract

The field of computational protein design is reaching its adolescence. Protein design algorithms have been applied to design or engineer proteins that fold, fold faster, catalyze, catalyze faster, signal, and adopt preferred conformational states. Further developments of scoring functions, sampling strategies, and optimization methods will expand the range of applicability of computational protein design to larger and more varied systems, with greater incidence of success. Developments in this field are beginning to have significant impact on biotechnology and chemical biology.

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Amino Acid Sequence Combinatorial Chemistry Techniques Computer-Aided Design Models, Molecular Molecular Sequence Data NIMA-Interacting Peptidylprolyl Isomerase Peptidylprolyl Isomerase Protein Conformation Proteins Surface Properties Journal Article Review

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C M Kraemer-Pecore, A M Wollacott, J R Desjarlais. 2001. Computational protein design.. https://doi.org/10.1016/s1367-5931(01)00267-8

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