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PubMed · 11742565

Endoxin:a major factor regulating cardiovascular system.

Y S Ke
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Abstract

Endoxin is a factor with a digitalis-like biological activity. It is a Na+ pump inhibitor and may be an endogenous medium of digitalis receptor. There are abnormal plasma levels of endoxin in some pathophysiologic states such as hypertension, acute myocardial infarction, arrhythmia, heart failure, etc. Some studies have demonstrated that the abnormal endoxin levels may be implicated in pathogenesis of these diseases or pathophysiologic process involved. Therefore, to clarify the effects of endoxin has much significance in understanding pathogenesis, prevention and treatment of hypertension and other cardiovascular diseases.

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AnimalsCardenolidesCardiomegalyCardiovascular SystemDiabetes MellitusDigoxinEnzyme InhibitorsHeart DiseasesHeart FailureHumansHypertensionMyocardial InfarctionPulmonary Heart DiseaseSaponinsSodium-Potassium-Exchanging ATPaseJournal ArticleResearch Support, Non-U.S. Gov'tReview

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Y S Ke. 2001. Endoxin:a major factor regulating cardiovascular system.. https://pubmed.ncbi.nlm.nih.gov/11742565/

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