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The Histone Database.

Steven Sullivan·Daniel W Sink·Kenneth L Trout·Izabela Makalowska·Patrick M Taylor·Andreas D Baxevanis·David Landsman
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Abstract

Histone proteins are often noted for their high degree of sequence conservation. It is less often recognized that the histones are a heterogeneous protein family. Furthermore, several classes of non-histone proteins containing the histone fold motif exist. Novel histone and histone fold protein sequences continue to be added to public databases every year. The Histone Database (http://genome.nhgri.nih.gov/histones/) is a searchable, periodically updated collection of histone fold-containing sequences derived from sequence-similarity searches of public databases. Sequence sets are presented in redundant and non-redundant FASTA form, hotlinked to GenBank sequence files. Partial sequences are also now included in the database, which has considerably augmented its taxonomic coverage. Annotated alignments of full-length non-redundant sets of sequences are now available in both web-viewable (HTML) and downloadable (PDF) formats. The database also provides summaries of current information on solved histone fold structures, post-translational modifications of histones, and the human histone gene complement.

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Amino Acid MotifsAnimalsChromosomal Proteins, Non-HistoneDatabases, ProteinGenetic VariationHistonesHumansInformation Storage and RetrievalInternetProtein ConformationProtein Processing, Post-TranslationalSequence AlignmentSequence HomologyJournal Article

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Steven Sullivan, Daniel W Sink, Kenneth L Trout, Izabela Makalowska, Patrick M Taylor, Andreas D Baxevanis, David Landsman. 2002-01-01. The Histone Database.. https://doi.org/10.1093/nar%2F30.1.341

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