Multiple calcium stores: separate but interacting.

H C Lee

doi:10.1126/stke.2000.40.pe1

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Multiple calcium stores: separate but interacting.

H C Lee

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Abstract

Multiple mechanisms exist for increasing the concentration of intracellular calcium. This Perspective by Lee is one in a series on intracellular calcium release mechanisms and focuses on the calcium store operated by nicotinic acid adenine dinucleotide phosphate (NAADP). The characterization of the NAADP-operated calcium store as separate from the inositol trisphosphate (IP(3))-operated and cyclic ADP-ribose (cADPR)-operated calcium stores is discussed. Lee also addresses the role of NAADP in regulating intracellular calcium fluctuations during fertilization and hormonal activation of pancreatic acinar cells.

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Adenosine Diphosphate Ribose Animals Calcium Calcium Signaling Cyclic ADP-Ribose Humans Inositol Phosphates NADP Journal Article Review

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H C Lee. 2000-07-11. Multiple calcium stores: separate but interacting.. https://doi.org/10.1126/stke.2000.40.pe1

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