Cellular screening assays using fluorescence microscopy.

R A Blake

doi:10.1016/s1471-4892(01)00092-3

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Cellular screening assays using fluorescence microscopy.

R A Blake

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Abstract

The recent development of automated fluorescence imaging systems has enabled fluorescence microscopy to be used for the purposes of compound screening. This information-rich technique has found various applications, including screening for the effect of kinase inhibitors on the cytoskeleton, agonist-stimulated receptor internalization, and protein phosphorylation and acetylation. The discovery of novel fluorescent proteins and new fluorescent dyes will find many applications in multichannel fluorescence imaging assays.

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Animals Cells Drug Evaluation, Preclinical Fluorescent Antibody Technique Fluorescent Dyes Humans Microscopy, Fluorescence Journal Article Review

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R A Blake. 2001. Cellular screening assays using fluorescence microscopy.. https://doi.org/10.1016/s1471-4892(01)00092-3

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