[A rapid method for detecting interconnections between functionally and/or evolutionary close biological sequences].

V D Gusev; L A Nemytikova; N A Chuzhanova

PubMed · 11771125

[A rapid method for detecting interconnections between functionally and/or evolutionary close biological sequences].

Abstract

It is now common practice to retrieve, by key words, highly specialized selections of sequences from general-purpose databases such as EMBL, GenBank, etc. The sequences included in a selection are often interconnected, which means that there are duplications, embeddings, intersections, homology, common structural elements. Knowledge of these interconnections is necessary for further processing of the sequences. We propose a rapid (single scan) method for identification of such interconnections by means of complexity analysis that generalizes the Lempel-Ziv approach. Analysis of a selection of 5'-flanking regions of vertebrate growth hormone genes from EMBL is presented as an example.

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Databases, Nucleic Acid Evolution, Molecular Repetitive Sequences, Nucleic Acid English Abstract Journal Article

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V D Gusev, L A Nemytikova, N A Chuzhanova. [A rapid method for detecting interconnections between functionally and/or evolutionary close biological sequences].. https://pubmed.ncbi.nlm.nih.gov/11771125/

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