Pharmacotherapy for erectile dysfunction.

T F Lue; K L Lee

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PubMed · 11775221

Pharmacotherapy for erectile dysfunction.

T F Lue·K L Lee

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Abstract

OBJECTIVE: To review current pharmacologic treatment options for erectile dysfunction. METHODS: Relevant literatures from the past two decades regarding the following treatments were reviewed: intracavemous injection, topical therapy, transurethral therapy and oral drugs. STUDY SELECTION: More than 125 originally identified articles were reviewed, and 45 were selected that especially addressed the stated purpose. RESULTS: Among the pharmacologic treatment options available, intracavemous injection therapy remains the most effective although the drop-out rate is high. Topical creams and gels have not been very successful. Transurethral alprostadil can be more effective if a constriction device is applied at the base of the penis. Oral sildenafil has the highest patient acceptance rate although systemic side effects can be a major drawback. CONCLUSIONS: Effective pharmacotherapies for ED of various etiologies are now available. However, proper evaluation of every patient should be performed before giving treatment so that a number of potentially life-threatening causes of erectile dysfunction would not be missed.

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Alprostadil Erectile Dysfunction Humans Male Nitric Oxide Donors Papaverine Phentolamine Piperazines Purines Sildenafil Citrate Sulfones Journal Article Review

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T F Lue, K L Lee. 2000. Pharmacotherapy for erectile dysfunction.. https://pubmed.ncbi.nlm.nih.gov/11775221/

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