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PubMed · 11780974

High-throughput structural proteomics using x-rays.

H Jhoti
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Abstract

Following the recent sequencing of the human genome, the focus has shifted from the DNA level to the protein level, with the goal of elucidating function. Technical developments in x-ray crystallography mean that the crystal structures of these new proteins can now been determined at an unprecedented rate, which assists in functional analysis and rational drug-design programmes.

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Crystallography, X-RayDrug DesignModels, MolecularProtein ConformationProteinsSoftwareJournal ArticleReview

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H Jhoti. 2001. High-throughput structural proteomics using x-rays.. https://doi.org/10.1016/s0167-7799(01)01791-7

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