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M Keller
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Abstract

Along with the detection of several genetic mutations that are associated with increased susceptibility for hereditary cancer syndromes, e. g. hereditary breast/ovarian and colorectal cancer, genetic tests are available for members of families at risk. Until now, the benefit in terms of prevention still needs to be confirmed. Furthermore, a variety of legal, ethical and psychosocial risks has to be considered, unless predictive genetic testing results in additional härm for individuals and families. Guidelines including Standards for genetic analyses and comprehensive counseling have been established worldwide aiming at the prevention of negative consequences for persons at risk. The knowledge collected in Psychooncology is applicable to the field of genetic counseling. During the pre-test-phase counseling aims at supporting the process of decision-making, both in individuals and in families. After disclosure of test results psychosocial support aims to enhance adjustment and communication within families. A small subgroup at risk for increased psychosocial distress warrants additional support. Efforts in research are needed to evaluate psychosocial issues during the process of decision-making and outcome, with adequate length of follow-up. Risk factors indicating poor psychosocial outcome need to be identified in order to develop appropriate ways of support.

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CancerDecision-makingEthicsFamily dynamicsGenetic counselingGenetic testingHereditaryPredictive testingPsychological distressPsychosocialEnglish AbstractJournal Article

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M Keller. 2000. [Not Available].. https://doi.org/10.13109/zptm.2000.46.1.80

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