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PubMed · 11795122

[Diabetic neuropathies].

J P Azulay·J Pouget
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Abstract

Peripheral nerve involvement is a frequent complication of type 1 and type 2 diabetes, and can induce major disability. Almost all types of clinical or electrophysiological disturbances may be present: mononeuropathy involving cranial nerves or a limb; multiple mononeuropathy; proximal acute radiculopathy; distal, symmetric, sensory polyneuropathy; autonomic neuropathy. Physiopathology intricates probably several mechanisms but metabolic dysregulation and ischemia are mainly involved. Despite numerous controlled clinical trials no treatment has demonstrated efficacy for peripheral neuropathy, excepting the optimization of diabetes equilibrium. However, symptomatic treatments are available, particularly for the management of neuropathic pain.

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AcetatesAminesAnimalsAnti-Inflammatory Agents, Non-SteroidalCarbamazepineControlled Clinical Trials as TopicCyclohexanecarboxylic AcidsDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Diabetic NeuropathiesDouble-Blind MethodElectrophysiologyGabapentinHumansHyperglycemiaImmunoglobulins, IntravenousLinoleic AcidPainPrognosisgamma-Aminobutyric AcidJournal Article

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J P Azulay, J Pouget. 2001-10-15. [Diabetic neuropathies].. https://pubmed.ncbi.nlm.nih.gov/11795122/

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