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PubMed · 11801325

Hedgehog patterns midbrain ARChitecture.

Robert Machold·Gord Fishell
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Abstract

Recent work from Agarwala et al. has uncovered exquisite ventral patterning in the mesencephalon. Using electroporation in chicks, they show that ectopic expression of Sonic Hedgehog (Shh) in dorsal mesencephalon can recapitulate this patterning in its entirety. These results are discussed in the context of the purported role of Shh as a morphogen.

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AnimalsBody PatterningBone Morphogenetic ProteinsCell DifferentiationChick EmbryoEmbryonic InductionHedgehog ProteinsHumansMesencephalonNeuronsNotochordTrans-ActivatorsJournal ArticleReview

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Robert Machold, Gord Fishell. 2002. Hedgehog patterns midbrain ARChitecture.. https://doi.org/10.1016/s0166-2236(00)01982-2

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