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PubMed · 11814564

Gap junctions and motor behavior.

Ole Kiehn·Matthew C Tresch
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Abstract

The production of any motor behavior requires coordinated activity in motor neurons and premotor networks. In vertebrates, this coordination is often assumed to take place through chemical synapses. Here we review recent data suggesting that electrical gap-junction coupling plays an important role in coordinating and generating motor outputs in embryonic and early postnatal life. Considering the recent demonstration of a prevalent expression of gap-junction proteins and gap-junction structures in the adult mammalian spinal cord, we suggest that neuronal gap-junction coupling might also contribute to the production of motor behavior in adult mammals.

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AnimalsGap JunctionsHumansInterneuronsMotor ActivityMotor NeuronsPsychomotor PerformanceSpinal CordSynaptic TransmissionJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.Review

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Ole Kiehn, Matthew C Tresch. 2002. Gap junctions and motor behavior.. https://doi.org/10.1016/s0166-2236(02)02038-6

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