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PubMed · 11820136

[Caries and fluoride].

C van Loveren
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Abstract

The cariostatic effect of fluoride is well documented, but the exact mechanisms of action are still subject of many studies. Re-evaluations of the clinical data of water fluoridation studies have confirmed that fluoride can have a pre-eruptive effect. But in general, the post-eruptive effects of low concentrations of fluoride on the de- and remineralisation processes are regarded to be of greater importance. Infrequent applications of concentrated fluoride solutions may only be effective in demineralised enamel. The Dutch national recommendations for the use of fluorides correspond well with the present views on the mechanisms of action of fluoride.

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Cariostatic AgentsDental CariesFluoridationFluoridesHumansNetherlandsPractice Guidelines as TopicRoot CariesEnglish AbstractJournal ArticleReview

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C van Loveren. 1992. [Caries and fluoride].. https://pubmed.ncbi.nlm.nih.gov/11820136/

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PubMed2007

Inhibition of erosive wear by fluoride varnish.

It has been suggested that fluoride products with a protective mechanical component are advantageous in the prevention of erosive wear. The aim of this study was to evaluate in situ the effect of fluoride varnish (FV) in the prevention of wear due to erosion and combined erosion and toothbrush abrasion. Eleven volunteers wore for 3 weeks, during working hours, appliances containing 2 control and 2 FV-treated human enamel samples. Erosion took place extraorally 3 times a day (5 min) in the soft drink Sprite. At the end of each experimental day one control and one FV sample (C-er+abr and FV-er+abr) were brushed (5 s) with fluoridated dentrifice. The remaining control and FV sample (C-er and FV-er) were left unbrushed. Enamel volume loss was quantified by optical profilometry at day 5, 10 and 15. A statistically significant progression in enamel loss was found for the C-er, C-er+abr and FV-er+abr groups (p < 0.001, p < 0.001 and p = 0.001, respectively) but not for the FV-er group (p = 0.053). The values of cumulative normalized volume loss (x10(8) mum) at day 15 were: C-er 5.53 +/- 2.14, C-er+abr 5.70 +/- 2.07, FV-er 0.79 +/- 0.67 and FV-er+abr 2.76 +/- 1.35. The FV-er and FV-er+abr groups showed significant lower volume loss than the C-er group (p < 0.001 and p = 0.005, respectively) and the C-er+abr group (p < 0.001 and p = 0.002, respectively). The results indicate that fluoride varnish is effective in the reduction of erosive wear.

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