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Fluoride modifies adhesion of Streptococcus pyogenes.

Junkai Cao·R J Doyle
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Abstract

Streptococcus pyogenes grown in the presence of subinhibitory concentrations of sodium fluoride had a diminished ability, compared to control cells, to adhere to buccal cells, collagen, fibronectin, and laminin. In addition, sodium fluoride was a competitive inhibitor of streptococcal adhesion to collagen and fibronectin, but not laminin. It is suggested that sodium fluoride may be useful in therapy or prophylaxis in infections involving group A streptococci.

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Anti-Bacterial AgentsBacterial AdhesionHumansSodium FluorideStreptococcus pyogenesJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.

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Junkai Cao, R J Doyle. 2002-01-14. Fluoride modifies adhesion of Streptococcus pyogenes.. https://doi.org/10.1111/j.1574-695x.2002.tb00550.x

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